CNS Neoplasm (Primary Tumor) - Miscellaneous

NCT03220035

Clinical Trial Information


Trial Number: NCT03220035 (ClinicalTrials.gov)
Disease Type:
  • CNS Neoplasm (Primary Tumor) - Miscellaneous
  • CNS-excluded Nervous System Neoplasm and Disorder - Neuroblastoma
  • Hematopoietic Neoplasm (excluding Leukemia, Lymphoma and Myeloma) - Miscellaneous
  • Hematopoietic Neoplasm/Lymphoma - Non-Hodgkin Lymphoma
  • Miscellaneous Neoplasm - Solid Tumor
Trial Title:
"NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice)- Phase 2 Subprotocol of Vemurafenib in Patients With Tumors Harboring BRAF V600 Mutations"
Study ID:
APEC1621G
Images are available?:
No
Is this a NCI-MATCH Trial?:
No


Datasets Linked to Trial

NCT03233204

Clinical Trial Information


Trial Number: NCT03233204 (ClinicalTrials.gov)
Disease Type:
  • CNS Neoplasm (Primary Tumor) - Miscellaneous
  • CNS-excluded Nervous System Neoplasm and Disorder - Neuroblastoma
  • Hematopoietic Neoplasm (excluding Leukemia, Lymphoma and Myeloma) - Miscellaneous
  • Hematopoietic Neoplasm/Lymphoma - Non-Hodgkin Lymphoma
  • Miscellaneous Neoplasm - Solid Tumor
Trial Title:
"NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice)- A Phase 2 Subprotocol of Olaparib in Patients With Tumors Harboring Defects in DNA Damage Repair Genes"
Study ID:
APEC1621H
Images are available?:
No
Is this a NCI-MATCH Trial?:
No


Datasets Linked to Trial

NCT03698994

Clinical Trial Information


Trial Number: NCT03698994 (ClinicalTrials.gov)
Disease Type:
  • CNS Neoplasm (Primary Tumor) - Miscellaneous
  • CNS-excluded Nervous System Neoplasm and Disorder - Neuroblastoma
  • Hematopoietic Neoplasm (excluding Leukemia, Lymphoma and Myeloma) - Miscellaneous
  • Hematopoietic Neoplasm/Lymphoma - Non-Hodgkin Lymphoma
  • Miscellaneous Neoplasm - Solid Tumor
Trial Title:
"NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of BVD-523FB (Ulixertinib) in Patients With Tumors Harboring Activating MAPK Pathway Mutations"
Study ID:
APEC1621J
Images are available?:
No
Is this a NCI-MATCH Trial?:
No


Datasets Linked to Trial

NCT03213665

Clinical Trial Information


Trial Number: NCT03213665 (ClinicalTrials.gov)
Disease Type:
  • CNS Neoplasm (Primary Tumor) - Miscellaneous
  • CNS-excluded Nervous System Neoplasm and Disorder - Neuroblastoma
  • Hematopoietic Neoplasm (excluding Leukemia, Lymphoma and Myeloma) - Miscellaneous
  • Hematopoietic Neoplasm/Lymphoma - Non-Hodgkin Lymphoma
  • Miscellaneous Neoplasm - Solid Tumor
Trial Title:
"NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of Tazemetostat in Patients With Tumors Harboring Alterations in EZH2 or Members of the SWI/SNF Complex"
Study ID:
APEC1621C
Images are available?:
No
Is this a NCI-MATCH Trial?:
No


Datasets Linked to Trial

NCT03213691

Clinical Trial Information


Trial Number: NCT03213691 (ClinicalTrials.gov)
Disease Type:
  • CNS Neoplasm (Primary Tumor) - Miscellaneous
  • CNS-excluded Nervous System Neoplasm and Disorder - Neuroblastoma
  • Hematopoietic Neoplasm (excluding Leukemia, Lymphoma and Myeloma) - Miscellaneous
  • Hematopoietic Neoplasm/Lymphoma - Non-Hodgkin Lymphoma
  • Miscellaneous Neoplasm - Solid Tumor
Trial Title:
NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of Selumetinib (AZD6244 Hydrogen Sulfate) in Patients With Tumors Harboring Activating MAPK Pathway Mutations
Study ID:
APEC1621E
Images are available?:
No
Is this a NCI-MATCH Trial?:
No


Datasets Linked to Trial

NCT00000008

Clinical Trial Information


Trial Number: NCT00000008 (ClinicalTrials.gov)
Disease Type:
  • CNS Neoplasm (Primary Tumor) - Miscellaneous
Trial Title:
Pinky and the Brain
Study ID:
CN1234
Images are available?:
No
Is this a NCI-MATCH Trial?:
No


Datasets Linked to Trial

NCT00369785

Clinical Trial Information


Trial Number: NCT00369785 (ClinicalTrials.gov)
Disease Type:
  • CNS Neoplasm (Primary Tumor) - Miscellaneous
  • Miscellaneous Neoplasm - Solid Tumor
Trial Title:
Phase III Double Blind, Placebo Controlled Study of Donepezil in the Irradiated Brain
Study ID:
WFU-91105
Images are available?:
No
Is this a NCI-MATCH Trial?:
No


Datasets Linked to Trial

Title Description
NCT00369785-D1 A total of 198 adult brain tumor survivors were randomly assigned to receive donepezil (5 mg for 6 weeks and 10 mg for 18 weeks) or placebo. Neurocognitive tests were assessed at baseline, 12 weeks post randomization, and 24 weeks post randomization. The primary aim of the study was to assess the effect of donepezil on a cognitive composite outcome (consisting of the average of eight standardized tests) at 24 weeks. A secondary aim was to assess the effect of donepezil on the individual tests. There was no significant effect of donepezil on the composite outcome. However, donepezil did significantly improve memory and motor speed/dexterity. This dataset contains all the data used in the publication PMID 25897156.

NCT03015701

Clinical Trial Information


Trial Number: NCT03015701 (ClinicalTrials.gov)
Disease Type:
  • CNS Neoplasm (Primary Tumor) - Miscellaneous
Trial Title:
Double Blind Randomized Trial of the Anti-Progestational Agent Mifepristone In The Treatment of Unresectable Meningioma
Study ID:
SWOG-9005 (S9005)
Images are available?:
No
Is this a NCI-MATCH Trial?:
No


Datasets Linked to Trial

Title Description
NCT03015701-D3 NCT03015701-D3-Dataset.csv provides adverse event data from both the blinded and open label treatment epochs.
NCT03015701-D2 NCT03015701-D2-Dataset.csv will provide descriptive information on the patients receiving open label mifepristone after progressing from blinded placebo.
NCT03015701-D1 The dataset NCT03015701-D1-Dataset.csv will allow users to reproduce efficacy analyses included in the aforementioned publication, which included primary and secondary efficacy results evaluating the mifepristone over placebo for the treatment of patients with unresectable meningioma in the SWOG phase III trial, S9005.
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