NCT00265850
Clinical Trial Information
Trial Number: NCT00265850 (ClinicalTrials.gov)
Disease Type:
- Gastrointestinal Neoplasm - Colorectal Cancer
Trial Title:
A Phase III Trial of Irinotecan / 5-FU / Leucovorin or Oxaliplatin / 5-FU/ Leucovorin With Bevacizumab, or Cetuximab (C225), or With the Combination of Bevacizumab and Cetuximab for Patients With Untreated Metastatic Adenocarcinoma of the Colon or Rectum
Study ID:
C80405
Images are available?:
No
Is this a NCI-MATCH Trial?:
No
Datasets Linked to Trial
| Title | Description |
|---|---|
| NCT00265850-D15 | Dataset NCT00265850-D15-Dataset.csv (nctn_cms) is one of 2 datasets associated with PubMed ID 31042420, a non-primary publication for trial C80405. This dataset contains the data to determine the predictive and prognostic value of the consensus molecular subtypes (CMSs) of colorectal cancer (CRC). Data from this trial’s primary publication can be found in NCT00265850-D1 through -D8. |
| NCT00265850-D14 | Dataset NCT00265850-D14-Dataset.csv (consort) is one of 2 datasets associated with PubMed ID 31042420, a non-primary publication from trial C80405. This dataset contains the data presented in the consort diagram for the secondary endpoint of determining the predictive and prognostic value of the consensus molecular subtypes (CMSs) of colorectal cancer. Data from this trial’s primary publication can be found in NCT00265850-D1 through -D8. Data that are identical to those presented in NCT00265850-D1 through -D8 are not duplicated in this submission. |
| NCT00265850-D13 | Dataset NCT00265850-D13-Dataset.csv (nctn_pcr) is one of 5 datasets associated with PubMed ID 30865548. This dataset contains data on the clinical characteristics, demographics, and endpoint analyses. For the 12 biomarker point mutation variables, missing values indicate that PCR testing was not performed for this patient. Otherwise, for clinical variables, missing values indicate that the data was not collected for this patient. This data submission, NCT00265850-D13-Dataset.csv, contains the data used to generate the results in PubMed ID 30865548, a non-primary publication from trial C80405. Data from this trial’s primary publication can be found in datasets NCT00265850-D1-Dataset.csv through NCT00265850-D8-Dataset.csv. Data that are identical to those presented in these available datasets are not duplicated in this submission. |
| NCT00265850-D12 | Dataset NCT00265850-D12-Dataset.csv (consort_ras) is one of 5 datasets associated with PubMed ID 30865548. This dataset allows you to identify which of the 1329 patients generated biomarker data. Of the 1329 patients, this dataset will allow you to identify which underwent PCR testing (n=843), and those which were included in the RAS analysis population. This data submission, NCT00265850-D12-Dataset.csv, contains the data used to generate the results in PubMed ID 30865548, a non-primary publication from trial C80405. Data from this trial’s primary publication can be found in datasets NCT00265850-D1-Dataset.csv through NCT00265850-D8-Dataset.csv. Data that are identical to those presented in these available datasets are not duplicated in this submission. |
| NCT00265850-D11 | Dataset NCT00265850-D11-Dataset.csv (consort_mut_load) is one of 5 datasets associated with PubMed ID 30865548. This dataset allows you to identify which of the 1329 patients generated biomarker data. Of the 1329 patients, this dataset will also allow you to identify which patients underwent Foundation Medicine Testing (n=559), of those which had mutation load result (n=536), and those that were included in the Mutation load analysis population (n=473). This data submission, NCT00265850-D11-Dataset.csv, contains the data used to generate the results in PubMed ID 30865548, a non-primary publication from trial C80405. Data from this trial’s primary publication can be found in datasets NCT00265850-D1-Dataset.csv through NCT00265850-D8-Dataset.csv. Data that are identical to those presented in these available datasets are not duplicated in this submission. |
| NCT00265850-D10 | NCT00265850-D10 (consort_msi) is one of 5 datasets associated with PubMed ID 30865548, a non-primary publication from trial C80405. This dataset allows you to identify which of the 1329 patients generated biomarker data. Of the 1329 patients, this dataset will allow you to identify which underwent MSI testing (n=797), which underwent Foundation Medicine Testing (n=559), which patients had either MSI OR Foundation Medicine testing (n=829), and which were ultimately included in the MSI analysis population (n=827). The wording in the consort diagram “Both MSI and Foundation Medicine Testing (n=829)” does not accurately describe the 829 patient subgroup. The 829 patients represent the patients with “Either MSI or Foundation Medicine Testing.” Data from this trial’s primary publication can be found in datasets NCT00265850-D1 through -D8. Data that are identical to those presented in these available datasets are not duplicated in this submission. |
| NCT00265850-D9 | Dataset NCT00265850-D9-Dataset.csv (consort_braf) is one of 5 datasets associated with PubMed ID 30865548. This dataset contains information to identify which (n=843) patients were included in the BRAF analysis population. This data submission, NCT00265850-D9-Dataset.csv, contains the data used to generate the results in PubMed ID 30865548, a non-primary publication from trial C80405. Data from this trial’s primary publication can be found in datasets NCT00265850-D1-Dataset.csv through NCT00265850-D8-Dataset.csv. Data that are identical to those presented in these available datasets are not duplicated in this submission. |
| NCT00265850-D8 | Dataset NCT00265850-D8-Dataset.csv (supplemental_modreasons) is one of 8 datasets associated with PubMed ID 28632865. This dataset contains information that will allow you to reproduce the frequency of treatment modifications from the supplemental Treatment Administration table. |
| NCT00265850-D7 | Dataset NCT00265850-D7-Dataset.csv (grade5) is one of 8 datasets associated with PubMed ID 28632865. This dataset contains information that will allow you to reproduce the number of deaths on treatment from the manuscript. |
| NCT00265850-D6 | Dataset NCT00265850-D6-Dataset.csv (table2) is one of 8 datasets associated with PubMed ID 28632865. This dataset contains information that will allow you to reproduce table 2 of the manuscript. |
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